1st FERO-MANGO Breast Cancer Research Project – Dr. Roger Gomis

The research focuses on the study of luminal breast cancer, one of the most common breast cancer subtypes, in which metastases have been observed to occur mainly in bone. This type of cancer can metastasise after long disease-free periods, causing death within a short period of time. In recent years, a possible interaction has been observed between the tumour cells that drive metastasis in this type of cancer and fibroblasts derived from MSC cells located in bone. These interactions affect the tumour and may underlie metastatic relapse and influence the disease’s response to systemic therapies. The project aims to study these interactions in order to understand them, identify therapeutic targets, and limit these cells’ ability to metastasise.